BDBM50490987 CHEMBL2376668

SMILES c1cc(c(cc1I)F)Nc2cc(cc(c2C(=O)N)OCC[C@H](CO)O)F

InChI Key InChIKey=HNTGGMMWHHPHAE-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490987   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50490987(CHEMBL2376668)Copy SMILESCopy InChI

Affinity DataIC50: 63nMAssay Description:Inhibition of MEK1 (unknown origin) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/31/2020
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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