BDBM50484553 CHEMBL1933936

SMILES CC1(Cc2c(c(sc2C(=O)NC1)Nc3ccc(cc3F)I)C(=O)N[C@@H]4CCCNC4)C

InChI Key InChIKey=YSSBOOQPHTZACI-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484553   

TargetDual specificity mitogen-activated protein kinase kinase 1/2(Human)
Ucb Pharma

Curated by ChEMBL

LigandBDBM50484553(CHEMBL1933936)Copy SMILESCopy InChI

Affinity DataIC50: 22nMAssay Description:Inhibition of human MEK using fluorescein-labelled Erk-tide as substrate after 20 mins by IMAP assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/29/2020
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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