BDBM50483172 CHEMBL1632158

SMILES COC(=O)CCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1

InChI Key InChIKey=RNXYMZNGMNWKMC-UHFFFAOYSA-N

Data  41 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 41 hits for monomerid = 50483172   

Target5-hydroxytryptamine receptor 4(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  0.107nMAssay Description:Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  316nMAssay Description:Binding affinity to 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  398nMAssay Description:Binding affinity to opioid receptor Sigma1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity to Histamine receptor H1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity to alpha2B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  2.51E+3nMAssay Description:Binding affinity to muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  3.16E+3nMAssay Description:Binding affinity to Histamine receptor H2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  3.16E+3nMAssay Description:Binding affinity to 5HT1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi:  6.31E+3nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to dopamine receptor D5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to muscarinic acetylcholine receptor M5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to beta2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to dopamine receptor D4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to alpha2A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to opioid receptor MORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to opioid receptor KORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT1E receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to alpha1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to beta1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to opioid receptor DORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to beta3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to dopamine receptor D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to Histamine receptor H3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to Histamine receptor H4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Drug Discovery Laboratory

Curated by ChEMBL
LigandPNGBDBM50483172(CHEMBL1632158)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity to muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed