BDBM50481827 CHEMBL5269187

SMILES CC(C)C1=C(Nc2c(cnn2C1=O)C#N)c3cnn(c3)C4CCN(CC4)C(=O)CCl

InChI Key InChIKey=UFTLGLOWZBFFND-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481827   

TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481827(CHEMBL5269187)
Affinity DataIC50: 65nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5B(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50481827(CHEMBL5269187)
Affinity DataIC50: 300nMAssay Description:Inhibition of KDM5B in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)