BDBM50481167 CHEMBL583865

SMILES CCNC(=O)[C@H]1c2ccccc2CN1C(=O)c3cc(c(cc3O)O)Cl

InChI Key InChIKey=QITRQXXSCAOQLZ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481167   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50481167(CHEMBL583865)
Affinity DataIC50: 300nMAssay Description:Inhibition of Hsp90 in human H1299 assessed as degradation of Hsp90 client protein AktMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)