BDBM50480483 6-O-Methylalaternin::CHEMBL556684

SMILES COc1cc(O)c2C(=O)c3c(O)c(O)c(C)cc3C(=O)c2c1

InChI Key InChIKey=IOPGGNYCFGEWPF-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50480483   

TargetFocal adhesion kinase 1(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 5.99E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 5.99E+3nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant B-RAF-V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant ERBB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 9.32E+3nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant CK2alpha1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant CDK2/CycAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of recombinant EPHB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of recombinant METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of recombinant COTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 8.32E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 8.99E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 9.99E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Heinrich-Heine-Universitat

Curated by ChEMBL
LigandPNGBDBM50480483(6-O-Methylalaternin | CHEMBL556684)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of recombinant CDK4/CycD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed