BDBM50468187 CHEMBL4288634

SMILES COc1ccc(nc1)-c1c([nH]c2cccnc12)-c1ccnc(NC(C)=O)c1

InChI Key InChIKey=VRPRBQAJAQCSCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468187   

TargetTGF-beta receptor type-1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50468187(CHEMBL4288634)
Affinity DataIC50: 6nMAssay Description:Inhibition of TGFbetaR1 T204D mutant (unknown origin) kinase domain after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50468187(CHEMBL4288634)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of wild type TGFbetaR2 (unknown origin) kinase domain after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed