BDBM50464196 CHEMBL1198227

SMILES c1ccc2c(c1)c(nc(n2)Nc3cccc(c3)Cl)NCc4ccco4

InChI Key InChIKey=KLRNKMZSARWWTH-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464196   

TargetSon of sevenless homolog 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50464196(CHEMBL1198227)
Affinity DataEC50:  9.70E+3nMAssay Description:Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)