BDBM50463900 CHEMBL4251258

SMILES Cc1c(c(on1)C)C2=CN(C(=O)C=C2)Cc3ccccc3

InChI Key InChIKey=CIJOVPIWGFQZFF-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463900   

TargetBromodomain-containing protein 4(Human)
Zenith Epigenetics

Curated by ChEMBL
LigandPNGBDBM50463900(CHEMBL4251258)
Affinity DataIC50: 80nMAssay Description:Inhibition of N-terminal His-tagged BRD4 (BD2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide after 30 mins by alpha-screen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Zenith Epigenetics

Curated by ChEMBL
LigandPNGBDBM50463900(CHEMBL4251258)
Affinity DataIC50: 230nMAssay Description:Inhibition of N-terminal His-tagged BRD4 (BD1) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide after 30 mins by alpha-screen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Zenith Epigenetics

Curated by ChEMBL
LigandPNGBDBM50463900(CHEMBL4251258)
Affinity DataIC50: 280nMAssay Description:Inhibition of N-terminal His-tagged BRD4 (BD1/BD2) (unknown origin) using biotinylated tetra-acetylated histone H4 peptide after 30 mins by alpha-scr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)