BDBM50463159 CHEMBL4241500

SMILES c1cc2c(cc1Cl)C(=O)CCS2

InChI Key InChIKey=OKHUUKHZUNKSQA-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463159   

TargetElongin-C(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50463159(CHEMBL4241500)
Affinity DataKd:  6.70nMAssay Description:Binding affinity to N-terminal His6 tagged VHL (54 to 213 residues)/ELoC (17 to 112 residues)/EloB (1 to 120 residues) (unknown origin) complex expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50463159(CHEMBL4241500)
Affinity DataKd:  6.70E+6nMAssay Description:Binding affinity to VHL (unknown origin) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)