BDBM50459416 CHEMBL4216473

SMILES CC(C)c1cn(nn1)CC(=O)Nc2ccc(cc2)Nc3c4c(cc(cc4F)OCCOC)ncn3

InChI Key InChIKey=FLJOFQUXYAWOPE-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50459416   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50459416(CHEMBL4216473)Copy SMILESCopy InChI

Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetMast/stem cell growth factor receptor Kit(Human)
Jinan University

Curated by ChEMBL

LigandBDBM50459416(CHEMBL4216473)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:Inhibition of wild type KIT (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/20/2024
Entry Details
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetPlatelet-derived growth factor receptor alpha(Human)
Jinan University

Curated by ChEMBL

LigandBDBM50459416(CHEMBL4216473)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/20/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL