BDBM50459208 CHEMBL4214342

SMILES Cc1ccc(cc1N2Cc3cnc(nc3N(C2=O)C)Nc4ccc(nc4)N5CCN(CC5)C(=O)C)NC(=O)c6cccc(c6)C(F)(F)F

InChI Key InChIKey=FCMNXGJPIJFWQV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459208   

TargetActivated CDC42 kinase 1(Human)
Korea University

Curated by ChEMBL

LigandBDBM50459208(CHEMBL4214342)Copy SMILESCopy InChI

Affinity DataIC50: 8nMAssay Description:Inhibition of ACK1 (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetMitogen-activated protein kinase kinase kinase kinase 2(Human)
Korea University

Curated by ChEMBL

LigandBDBM50459208(CHEMBL4214342)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Inhibition of GCK (unknown origin) by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL