BDBM50458541 CHEMBL4214963::US11999723, Compound 5

SMILES OC(=O)c1cccc(c1)-c1cn[nH]c1

InChI Key InChIKey=BXSUQWZHUHROLP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458541   

TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50458541(CHEMBL4214963 | US11999723, Compound 5)
Affinity DataKi:  1.13E+5nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli using HPP as substrate preincubated for 20 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50458541(CHEMBL4214963 | US11999723, Compound 5)
Affinity DataKi:  1.13E+5nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using the substrate 4-hydroxyphenyl pyruvic acid (HPP) in a procedure largely adapted from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
Go to US Patent