BDBM50457621 CHEMBL578530::GNF-Pf-5378

SMILES C[C@@H]1CCC[C@H](O1)C[C@H]2Cc3cc(cc(c3C(=O)O2)O)O

InChI Key InChIKey=WOMKDMUZNBFXKG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457621   

TargetLysine--tRNA ligase(Plasmodium falciparum (isolate 3D7))
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50457621(CHEMBL578530 | GNF-Pf-5378)
Affinity DataIC50: 7.25E+3nMAssay Description:Inhibition of Plasmodium falciparum KRS expressed in Escherichia coli BL21 using tRNA(Lys) as substrate after 45 mins in presence of L-lysine by AMP-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine--tRNA ligase(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50457621(CHEMBL578530 | GNF-Pf-5378)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human KRS expressed in Escherichia coli BL21 using tRNA(Lys) as substrate after 1 hr in presence of L-lysine by AMP-GLO assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed