BDBM50455885 CHEMBL1471153

SMILES c1ccc2c(c1)C(=O)N(C=N2)CC(=O)O

InChI Key InChIKey=BBBICQPTZBHLBM-UHFFFAOYSA-N

Data  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50455885   

TargetHistone deacetylase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50455885(CHEMBL1471153)
Affinity DataIC50: 3.20E+5nMAssay Description:Displacement of N-terminal FITC-labeled RLRGG from N-terminal AviTag/C-terminal His6-tagged HDAC6 ZnF-UBD (unknown origin) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 5(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50455885(CHEMBL1471153)
Affinity DataKd:  2.20E+5nMAssay Description:Binding affinity to N-terminal Avitag-fused His6-tagged USP5 ZnF-UBD (unknown origin) (171 to 290 residues) labelled with 5-fluorotryptophan expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUbiquitin carboxyl-terminal hydrolase 5(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50455885(CHEMBL1471153)
Affinity DataKd:  2.20E+5nMAssay Description:Binding affinity to N-terminal Avitag-fused His6-tagged USP5 ZnF-UBD (unknown origin) (171 to 290 residues) labelled with 5-fluorotryptophan expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)