BDBM50455493 CHEMBL4213809

SMILES CC(=O)N1[C@H](CN(Cc2ccccc2CO)c2cc(ccc12)-c1cnc(nc1)C(N)=O)C1CC1

InChI Key InChIKey=JVAKWUYUZCOCKR-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50455493   

TargetBromodomain-containing protein 2(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human BRD2 BD1 after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50: 100nMAssay Description:Inhibition of BRDT BD2 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50: 794nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50: 100nMAssay Description:Inhibition of human BRD2 BD2 after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50: 32nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50: 501nMAssay Description:Inhibition of BRDT BD1 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50: 50nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y97A mutant BD2 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPeregrin(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455493(CHEMBL4213809)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of Alexa 647 ligand from 6H-Flag-Tev-BRPF1 (622 to 738 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed