BDBM50454869 CHEMBL4206212

SMILES CNC(=O)c1cc(ccn1)Oc2ccc(c(c2)F)NC(=O)Nc3ccc(c(c3)F)SCC(=O)O

InChI Key InChIKey=LUCVAGIVDZCQRA-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454869   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50454869(CHEMBL4206212)
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of wild type recombinant human His6-tagged RIPK2 using RS repeat peptide substrate incubated for 2 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50454869(CHEMBL4206212)
Affinity DataIC50: 4.87E+3nMAssay Description:Inhibition of recombinant human His6-tagged RIPK2 R171C mutant using RS repeat peptide substrate incubated for 2 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)