BDBM50453305 CHEMBL4212397

SMILES CC(C)c1cc(NNC(=O)Nc2cc(Cl)nc(OCC3CC3)c2)nc2n(C)nc(C)c12

InChI Key InChIKey=KATYKXXGQBFJLO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50453305   

LigandChemical structure of BindingDB Monomer ID 50453305BDBM50453305(CHEMBL4212397)
Affinity DataIC50: 57nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR2 expressed in Chem1 cell membranes co-expressing Galpha15 pretreated for 30 mins followed by [32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453305BDBM50453305(CHEMBL4212397)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR3 expressed in Chem1 cell membranes co-expressing Galpha15 pretreated for 30 mins followed by [32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453305BDBM50453305(CHEMBL4212397)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR4 expressed in cell membranes pretreated for 30 mins followed by [32P]S1P addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453305BDBM50453305(CHEMBL4212397)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR1 expressed in CHOK1 cell membranes pretreated for 30 mins followed by [32P]S1P addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453305BDBM50453305(CHEMBL4212397)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from recombinant human S1PR5 expressed in cell membranes pretreated for 30 mins followed by [32P]S1P addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed