BDBM50450890 CHEMBL4206604

SMILES CC(C)n1cnc2c1nc(nc2Nc3ccc(cc3)N4CCN(CC4)C)N[C@H]5CCN(C5)C(=O)C

InChI Key InChIKey=ACTNABQUCQIOKX-UHFFFAOYSA-N

Data  1 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50450890   

TargetEpidermal growth factor receptor(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50450890(CHEMBL4206604)
Affinity DataKi:  161nMAssay Description:Inhibition of EGFR T790M/L858R double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)