BDBM50450131 CHEMBL4164423

SMILES Cc1cc(c(nc1)Oc2ccc3c(c2)n(c(n3)COc4cccc(c4)C(=O)O)C)C

InChI Key InChIKey=GEGLFSVXCSGSOB-UHFFFAOYSA-N

Data  5 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50450131   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50450131(CHEMBL4164423)
Affinity DataEC50:  41nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50450131(CHEMBL4164423)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARalpha LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50450131(CHEMBL4164423)
Affinity DataEC50:  41nMAssay Description:Agonist activity at recombinant human GAL4-DBD fused PPARgamma LBD expressed in COS7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50450131(CHEMBL4164423)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human Gal4 fused PPARalpha LBD (unknown origin) expressed in COS-7 cells incubated for 24 hrs by firefly luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50450131(CHEMBL4164423)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human Gal4-DBD fused PPARgamma LBD (unknown origin) expressed in COS-7 cells incubated for 24 hrs by firefly luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)