BDBM50449704 CHEMBL4079934

SMILES Cc1cc(nc(n1)SCC(=O)Nc2cccc(c2)COc3ccccc3)C

InChI Key InChIKey=UTHZHWWWTOWRMG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449704   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
West China School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50449704(CHEMBL4079934)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of recombinant His-tagged SIRT2 (56 to 356 residues) (unknown origin) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
West China School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50449704(CHEMBL4079934)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of recombinant His-tagged SIRT2 (56 to 356 residues) (unknown origin) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)