BDBM50446989 CHEMBL3116056

SMILES Cc1csc2c1nc(nc2Nc3cn(cn3)C)N[C@@H](C)c4ncc(cn4)F

InChI Key InChIKey=DVWTWOHVDUVPJV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446989   

TargetTyrosine-protein kinase JAK3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446989(CHEMBL3116056)
Affinity DataIC50: 3.93E+3nMAssay Description:Inhibition of Jak3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50446989(CHEMBL3116056)
Affinity DataIC50: 4nMAssay Description:Inhibition of Jak2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)