BDBM50444385 CHEMBL3094442

SMILES COc1ncc2c(n1)NC(=O)C(=C2)C(=O)Nc3cc(ccc3Cl)C(=O)OC

InChI Key InChIKey=SIVLENRHVVVPKJ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50444385   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Hoffmann-La Roche

Curated by ChEMBL

LigandBDBM50444385(CHEMBL3094442)Copy SMILESCopy InChI

Affinity DataIC50: 97nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Hoffmann-La Roche

Curated by ChEMBL

LigandBDBM50444385(CHEMBL3094442)Copy SMILESCopy InChI

Affinity DataIC50: 134nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL