BDBM50444085 CHEMBL3092785::US9649309, Compound UNC1917A

SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccccn1

InChI Key InChIKey=DMDQOCLVSGUEJT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444085   

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50444085(CHEMBL3092785 | US9649309, Compound UNC1917A)
Affinity DataIC50: 630nMAssay Description:Inhibition of Tyro-3 kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50444085(CHEMBL3092785 | US9649309, Compound UNC1917A)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of Axl kinase (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50444085(CHEMBL3092785 | US9649309, Compound UNC1917A)
Affinity DataIC50: 17nMAssay Description:Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50444085(CHEMBL3092785 | US9649309, Compound UNC1917A)
Affinity DataIC50: 55nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
Go to US Patent