BDBM50442897 BILIRUBIN

SMILES Cc1c(c([nH]c1/C=C\2/C(=C(C(=O)N2)C=C)C)Cc3c(c(c([nH]3)/C=C\4/C(=C(C(=O)N4)C)C=C)C)CCC(=O)O)CCC(=O)O

InChI Key InChIKey=BPYKTIZUTYGOLE-UHFFFAOYSA-N

Data  3 KI  2 IC50

PDB links: 13 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50442897   

LigandPNGBDBM50442897(BILIRUBIN)
Affinity DataIC50: 3.39E+3nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50442897(BILIRUBIN)
Affinity DataIC50: 1.32E+3nMAssay Description:pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50442897(BILIRUBIN)
Affinity DataKi:  720nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50442897(BILIRUBIN)
Affinity DataKi:  2.63E+3nMAssay Description:Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSolute carrier organic anion transporter family member(Zebrafish)
Rudjer Boskovic Institute

LigandPNGBDBM50442897(BILIRUBIN)
Affinity DataKi:  1.45E+4nMAssay Description:In the inhibition experiments, the cells were preincubated for 20 s with test compounds, followed by a 5-min incubation with [3H]E3S (5 nM) or 30-min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2017
Entry Details Article
PubMed