BDBM50442698 CHEMBL2442287

SMILES CN(C)CCNc1ccn2c(n1)c(cn2)c3c[nH]nc3

InChI Key InChIKey=PSIMDRXAPBUVNE-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442698   

TargetSerine/threonine-protein kinase pim-2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442698(CHEMBL2442287)
Affinity DataIC50: 185nMAssay Description:Inhibition of Pim2 (unknown origin) using STK1 as substrate preincubated for 30 mins followed by substrate and ATP addition after 60 mins by HTRF ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442698(CHEMBL2442287)
Affinity DataIC50: 7nMAssay Description:Inhibition of Pim1 (unknown origin) using STK3 as substrate preincubated for 30 mins followed by substrate and ATP addition after 45 mins by HTRF ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)