BDBM50442692 CHEMBL2442317

SMILES c1ccc2cc(ccc2c1)c3cnn4c3nc(cc4)N[C@@H]5CCCC[C@H]5N

InChI Key InChIKey=LODPYXJMYAQIRB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442692   

TargetSerine/threonine-protein kinase pim-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442692(CHEMBL2442317)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Pim1 (unknown origin) using STK3 as substrate preincubated for 30 mins followed by substrate and ATP addition after 45 mins by HTRF ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442692(CHEMBL2442317)
Affinity DataIC50: 157nMAssay Description:Inhibition of Pim2 (unknown origin) using STK1 as substrate preincubated for 30 mins followed by substrate and ATP addition after 60 mins by HTRF ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed