BDBM50435727 CHEMBL2392545

SMILES CN1CCC(CC1)NC(=O)c2cc(c(cc2F)Nc3ncc4c(n3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC

InChI Key InChIKey=GWRSATNRNFYMDI-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50435727   

TargetSerine/threonine-protein kinase PLK1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50435727(CHEMBL2392545)
Affinity DataIC50: 2nMAssay Description:Inhibition of PLK1 (unknown origin) using biotin-AGAGTVPESIHSFIGDGLV as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PLK1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50435727(CHEMBL2392545)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PLK1(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50435727(CHEMBL2392545)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PLK1 (unknown origin) using biotinylated-AGAGTVPESIHSFIGDGLV as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)