BDBM50433906 CHEMBL2380583

SMILES CCOc1cc2c(cc1c3cnn(c3)C)[nH]nc2c4ccc(c(c4)S(=O)(=O)N)C

InChI Key InChIKey=CITPEYUXGCJVRV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433906   

TargetDual specificity protein kinase TTK(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50433906(CHEMBL2380583)
Affinity DataIC50: 198nMAssay Description:Inhibition of FLAG-tagged MPS1 phosphorylation in human RERF-LC-AI Tet-off cells after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase TTK(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50433906(CHEMBL2380583)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of MPS1 (unknown origin) using biotin-labeled AGAGLARHTDDEMTGYVA as substrate after 90 mins by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)