BDBM50429908 CHEMBL2333411

SMILES c1ccc2c(c1)nc(s2)Sc3c(c(c(c(c3F)F)S(=O)(=O)N)F)F

InChI Key InChIKey=YVWIZEXTHJMGAV-UHFFFAOYSA-N

Data  5 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50429908   

TargetCarbonic anhydrase 13(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429908(CHEMBL2333411)
Affinity DataKd:  0.25nMpH: 7.0Assay Description:Binding affinity to human recombinant CA13 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429908(CHEMBL2333411)
Affinity DataKd:  200nMpH: 7.0Assay Description:Binding affinity to human recombinant CA12 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429908(CHEMBL2333411)
Affinity DataKd:  0.220nMpH: 7.0Assay Description:Binding affinity to human recombinant CA7 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429908(CHEMBL2333411)
Affinity DataKd:  1.10nMpH: 7.0Assay Description:Binding affinity to human recombinant CA2 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Vilnius University Institute of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50429908(CHEMBL2333411)
Affinity DataKd:  1.10nMpH: 7.0Assay Description:Binding affinity to human recombinant CA1 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed