BDBM50429616 CHEMBL2334583

SMILES c1cc2c(cc1Br)c-3c([nH]2)CCCc4c3nc(nc4)N

InChI Key InChIKey=MEOWHQIIZUZBTO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50429616   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Amgen

Curated by ChEMBL

LigandBDBM50429616(CHEMBL2334583)Copy SMILESCopy InChI

Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of NIK in human HT-29 cells assessed as LTalpha/beta2-induced p100 processing to NFkappaB2 preincubated for 30 mins before LTalpha/beta2 s...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetMitogen-activated protein kinase kinase kinase 14(Human)
Amgen

Curated by ChEMBL

LigandBDBM50429616(CHEMBL2334583)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL