BDBM50429228 CHEMBL2332789

SMILES Cc1cc(nc(c1)N)C[C@@H]2CNC[C@@H]2OCCN[C@H](C)Cc3cccc(c3)F

InChI Key InChIKey=AUSIEXNWJKDTQY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50429228   

TargetNitric oxide synthase, brain(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  70nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  71nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  860nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  7.60E+3nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of bovine eNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50429228(CHEMBL2332789)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of bovine eNOS expressed in Escherichia coli using L-arginine as substrate assessed as formation of nitric oxide by hemoglobin capture ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed