BDBM50425832 CHEMBL2312290

SMILES COc1ccc(CCNc2ncc(C(=O)NCCCN3CCCC3=O)c(NC3CCCC3)n2)cc1OC

InChI Key InChIKey=BQICBFKSXAVIBF-UHFFFAOYSA-N

Data  22 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50425832   

TargetMitogen-activated protein kinase 1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of MAPK1/ERK2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 270nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetTyrosine-protein kinase ABL1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 910nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetRAC-alpha serine/threonine-protein kinase(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetSerine/threonine-protein kinase Chk2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetCasein kinase I isoform delta(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CK1delta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetEpidermal growth factor receptor(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IKKi (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetInsulin receptor(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of INSR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetSerine/threonine-protein kinase Chk1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MAPKAP-K2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetSerine/threonine-protein kinase pim-2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of PIM2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetProtein kinase C zeta type(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PKCzeta (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetSerine/threonine-protein kinase Sgk1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SGK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of HGFR (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
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TargetTyrosine-protein kinase receptor UFO(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 61nMAssay Description:Inhibition of Axl (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetTyrosine-protein kinase Mer(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 126nMAssay Description:Inhibition of Mer (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50425832(CHEMBL2312290)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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