BDBM50415620 CHEMBL1088633

SMILES COc1cc2CCN=C(c3cccc(Cl)c3)c2cc1Cl

InChI Key InChIKey=FRZUSJCWOONEQS-UHFFFAOYSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50415620   

LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKKalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal GST-tagged human full length Erk2 by radiometric filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal histidine-tagged human full length JNK1-alpha-1 by radiometric filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of N-terminal GST-tagged p38alpha expressed in Escherichia coli by fluorescence anisotropyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MLK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 251nMAssay Description:Inhibition of N-terminal His(6)-tagged truncated human JNK3 transfected in baculovirus expression system by fluorescence anisotropyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-FmsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 126nMAssay Description:Inhibition of N-terminal histidine-tagged human full length JNK3 by radiometric filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50415620(CHEMBL1088633)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of N-terminal histidine-tagged human full length JNK2-alpha-2 by radiometric filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed