BDBM50398699 CHEMBL214393

SMILES C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O

InChI Key InChIKey=DJJCXFVJDGTHFX-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50398699   

TargetProtein argonaute-2(Human)
Gifu University

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to human Argonaut protein 2 PAZ domain assessed as dissociation constant by using isothermal titration microcalorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataIC50: 5.00E+6nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetUridine 5'-monophosphate synthase(Human)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibition of human ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetOrotidine-5'-phosphate decarboxylase(malaria parasite P. falciparum)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
University Health Network

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed