BDBM50396261 CHEMBL2172323

SMILES COC(=O)C1CCC(CC1)n2c3cc(ccc3nc2NC(=O)c4ccccc4)CN5CCCCC5

InChI Key InChIKey=NFTRTTWPZBZTLY-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396261   

TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50396261(CHEMBL2172323)
Affinity DataIC50: 54nMAssay Description:Inhibition of ALK Tyr1604 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50396261(CHEMBL2172323)
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50396261(CHEMBL2172323)
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)