BDBM50391949 CHEMBL2147768

SMILES COc1ccc2c(c1CN3CCNCC3)O/C(=C\c4c[nH]c5c4ccnc5)/C2=O

InChI Key InChIKey=GZVLKFFYCJUAPT-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391949   

TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391949(CHEMBL2147768)
Affinity DataIC50: 92nMAssay Description:Inhibition of PIM1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391949(CHEMBL2147768)
Affinity DataIC50: 44nMAssay Description:Inhibition of PIM3 (unknown origin) using FL-Peptide 1 (5-FAM-AKRRRLSSLRA-COOH) substrate incubated for 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391949(CHEMBL2147768)
Affinity DataIC50: 92nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)