BDBM50391936 CHEMBL2147758

SMILES c1ccc2c(c1)c(c[nH]2)/C=C\3/C(=O)c4ccc(c(c4O3)CN5CCCCCC5)O

InChI Key InChIKey=IARYZBOIUVHJGF-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391936   

TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391936(CHEMBL2147758)
Affinity DataIC50: 410nMAssay Description:Inhibition of PIM1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391936(CHEMBL2147758)
Affinity DataIC50: 4.10E+5nMAssay Description:Inhibition of full length human PIM1 expressed in Escherichia coli BL21 (DE3) preincubated for 0.5 hrs followed by substrate addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)