BDBM50390969 PYRAZOLE

SMILES c1c[nH]nc1

InChI Key InChIKey=WTKZEGDFNFYCGP-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 Kd

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50390969   

TargetLysine-specific demethylase 4C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50390969(PYRAZOLE)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAlcohol dehydrogenase S chain(Horse)
TBA

Curated by ChEMBL
LigandPNGBDBM50390969(PYRAZOLE)
Affinity DataKd:  200nMAssay Description:Inhibition of horse liver alcohol dehydrogenase using ethanol as substrate assessed as dissociation constant by spectrophotometric titration in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlcohol dehydrogenase S chain(Horse)
TBA

Curated by ChEMBL
LigandPNGBDBM50390969(PYRAZOLE)
Affinity DataKi:  1.86E+3nMAssay Description:Inhibitory activity against horse liver alcohol dehydrogenase (ADH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 4C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50390969(PYRAZOLE)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed