BDBM50384734 CHEMBL2037211

SMILES CN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)c1

InChI Key InChIKey=JECVRFZSSMBKTJ-UHFFFAOYSA-N

Data  19 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50384734   

TargetMast/stem cell growth factor receptor Kit(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:Inhibition of Tel-fused KIT in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
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TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Tel-fused FMS in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
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TargetHigh affinity nerve growth factor receptor(Human)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 7nMAssay Description:Inhibition of TRKA by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
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TargetBDNF/NT-3 growth factors receptor(Human)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 7nMAssay Description:Inhibition of TRKB by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
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TargetCytoplasmic tyrosine-protein kinase BMX(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of Tel-fused BMX in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetVascular endothelial growth factor receptor 1(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Tel-fused FLT1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
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TargetReceptor-type tyrosine-protein kinase FLT3(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Tel-fused FLT3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
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TargetInsulin-like growth factor 1 receptor(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Tel-fused IGF1R in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetInsulin receptor(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Tel-fused INSR in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
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TargetMitogen-activated protein kinase 9(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Tel-fused JNK2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetProto-oncogene tyrosine-protein kinase ROS(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetHepatocyte growth factor receptor(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Tel-fused MET in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetTyrosine-protein kinase Lyn(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Tel-fused LYN in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
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TargetPlatelet-derived growth factor receptor beta(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:Inhibition of Tel-fused PDGFRbeta in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetProto-oncogene tyrosine-protein kinase receptor Ret(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 800nMAssay Description:Inhibition of Tel-fused RET in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetMacrophage-stimulating protein receptor(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of Tel-fused RON in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetProto-oncogene tyrosine-protein kinase Src(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Tel-fused SRC in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetTyrosine-protein kinase receptor Tie-1(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of Tel-fused TIE1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
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TargetTyrosine-protein kinase ZAP-70(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50384734(CHEMBL2037211)Copy SMILESCopy InChI

Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Tel-fused ZAP70 in mouse BA/F3 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
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