BDBM50384720 CHEMBL2037220

SMILES CN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1cccc(Nc2ccc3\C(=C\c4cc(c[nH]4)C(O)=O)C(=O)Nc3c2)c1

InChI Key InChIKey=FWZMHIPXROINAE-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50384720   

TargetMitogen-activated protein kinase 9(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Tel-fused JNK2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 17nMAssay Description:Inhibition of TRKB by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Tel-fused ALK in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused BMX in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEphrin type-A receptor 3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Tel-fused EPHA3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Tel-fused TIE1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Tel-fused FLT3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of Tel-fused FMS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused IGF1R in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetInsulin receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused INSR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Tel-fused FLT1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 46nMAssay Description:Inhibition of Tel-fused KIT in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused LYN in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 100nMAssay Description:Inhibition of Tel-fused RET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused RON in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused SRC in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused FGFR3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tel-fused FGFR4 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fgr(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50384720(CHEMBL2037220)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of Tel-fused FGR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed