BDBM50384714 CHEMBL2037200

SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1

InChI Key InChIKey=KGBPLKOPSFDBOX-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50384714   

LigandPNGBDBM50384714(CHEMBL2037200)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384714(CHEMBL2037200)
Affinity DataIC50: 134nMAssay Description:Inhibition of Flt3 using EAIYAAPFAKKK as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384714(CHEMBL2037200)
Affinity DataIC50: 16nMAssay Description:Inhibition of Pim3 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384714(CHEMBL2037200)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Flt3 phosphorylation at Y591 in human MV411 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384714(CHEMBL2037200)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384714(CHEMBL2037200)
Affinity DataIC50: 5nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50384714(CHEMBL2037200)
Affinity DataKi:  5nMAssay Description:Reversible inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed