BDBM50383117 CHEMBL2031737

SMILES C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)C(=O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=GPZMWOXSIRVXQW-UHFFFAOYSA-N

Data  38 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 50383117   

TargetHistamine H3 receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to human H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  137nMAssay Description:Binding affinity to human recombinant DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  336nMAssay Description:Binding affinity to human recombinant M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  415nMAssay Description:Binding affinity to human recombinant M4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  512nMAssay Description:Binding affinity to human recombinant M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  681nMAssay Description:Binding affinity to human recombinant M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  923nMAssay Description:Binding affinity to human recombinant H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  931nMAssay Description:Binding affinity to human recombinant M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  1.36E+3nMAssay Description:Binding affinity to human recombinant 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  5.24E+3nMAssay Description:Binding affinity to human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi:  7.06E+3nMAssay Description:Binding affinity to human recombinant H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant alpha2C adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant alpha2A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant alpha1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant alpha1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant sigma1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant beta1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant beta3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant Dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant Dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant Dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant Dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant Dopamine D5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant beta2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant 5HT5A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant 5HT1E receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant alpha1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50383117(CHEMBL2031737)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant alpha2B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed