BDBM50377852 CHEMBL261655

SMILES COc1cccc(CN2C[C@H](NC2=O)C(=O)N[C@@H](Cc2ccccc2)[C@H](O)CNCc2cccc(c2)N(C)C)c1

InChI Key InChIKey=MCBWJRZWLSXSBN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50377852   

TargetBeta-secretase 1(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377852(CHEMBL261655)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of human BACE1 by SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCathepsin D(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377852(CHEMBL261655)
Affinity DataKi:  195nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Lg Life Sciences

Curated by ChEMBL
LigandPNGBDBM50377852(CHEMBL261655)
Affinity DataKi:  449nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed