BDBM50370587 CEFAZOLIN

SMILES Cc1nnc(s1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)Cn4cnnn4)SC2)C(=O)O

InChI Key InChIKey=MLYYVTUWGNIJIB-UHFFFAOYSA-N

Data  7 KI

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50370587   

TargetSolute carrier family 22 member 6(Human)
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50370587(CEFAZOLIN)
Affinity DataKi:  180nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Human)
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50370587(CEFAZOLIN)
Affinity DataKi:  550nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 22 member 11(Human)
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50370587(CEFAZOLIN)
Affinity DataKi:  1.74E+3nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSolute carrier family 15 member 1(Human)
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50370587(CEFAZOLIN)
Affinity DataKi: >3.00E+7nMAssay Description:Binding affinity against membrane transport protein PEPT1 in human Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Rat)
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50370587(CEFAZOLIN)
Affinity DataKi:  4.50E+5nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details
PubMed
TargetSolute carrier family 22 member 8(Rat)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50370587(CEFAZOLIN)
Affinity DataKi:  7.80E+5nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Rat)
Kyorin University

Curated by ChEMBL
LigandPNGBDBM50370587(CEFAZOLIN)
Affinity DataKi:  5.60E+5nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed