BDBM50370453 LACTOSE::Lactose, anhydrous

SMILES C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)O)CO)O)O)O)O

InChI Key InChIKey=GUBGYTABKSRVRQ-UHFFFAOYSA-N

Data  6 IC50  11 Kd

PDB links: 14 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50370453   

TargetGalectin-9(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  2.30E+4nMAssay Description:Binding affinity to galectin 9N terminal domain at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  2.31E+5nMAssay Description:Binding affinity to human galactin-3 assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetGalectin-8(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  9.10E+4nMAssay Description:Binding affinity to human galactin-8 N terminal domain assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGalectin-8(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  3.79E+4nMAssay Description:Binding affinity to N-terminal domain of human galectin-8 (8-154 residues) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGalectin-3(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of galectin-3 in C57BL/6 mouse jejunum using SK-5100 as substrate incubated for 30 mins by VAA staining based microscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetBeta-galactoside-binding lectin(Chicken)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibition of binding of biotinylated chicken galectin-1B to surface immobilized asialofetuin by solid phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGalectin(Chicken)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of binding of biotinylated chicken galectin-3 to surface immobilized asialofetuin by solid phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGalectin(Chicken)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 4.50E+6nMAssay Description:Inhibition of binding of biotinylated truncated chicken galectin-3 to surface immobilized asialofetuin by solid phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGalectin-7(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  1.10E+5nMAssay Description:Binding affinity to galectin 7 at 0 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  2.30E+5nMAssay Description:Binding affinity to galectin-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetGalectin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of recombinant galectin 1 in human O type red blood cells by hemagglutinination assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of recombinant galectin 3 in human O type red blood cells by hemagglutinination assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGalectin-8(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  6.20E+4nMAssay Description:Binding affinity to galectin 8N terminal domain at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGalectin-3(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  1.10E+5nMAssay Description:Binding affinity to galectin 3 at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  4.20E+5nMAssay Description:Binding affinity to galectin 1 at 20 degC by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetGalectin-3(Mouse)
Ludwig-Maximilians-University Munich

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  2.22E+5nMAssay Description:Dissociation constant for mouse Galectin-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetGalectin-3(Human)
Lund University

Curated by ChEMBL
LigandPNGBDBM50370453(Lactose, anhydrous | LACTOSE)
Affinity DataKd:  9.26E+4nMAssay Description:Inhibition of human recombinant wild type galectin 3 after 60 mins by surface plasmon resonance immunosensor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2016
Entry Details Article
PubMed