BDBM50366289 CHEMBL4163317

SMILES CN1CCN(CC1)Cc2cn(c3c2ccc(c3)NC(=S)NCCc4c[nH]c5c4cccc5)CC(=O)N6CCOCC6

InChI Key InChIKey=KSDJEFBPBCSCLA-UHFFFAOYSA-N

Data  1 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50366289   

TargetB-cell lymphoma 6 protein(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50366289(CHEMBL4163317)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to isotopically labeled and N-terminal thioredoxin-His6 tag with N-terminal thrombin-cleavage site containing recombinant BCL6 BTB d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50366289(CHEMBL4163317)
Affinity DataKd:  3.60E+4nMAssay Description:Binding affinity to N-terminal thioredoxin-His6 tag with N-terminal thrombin-cleavage site containing recombinant BCL6 BTB domain C8Q/C67R/C84N/E99V ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50366289(CHEMBL4163317)
Affinity DataIC50: 2.70E+4nMAssay Description:Binding affinity to N-terminal thioredoxin-His6 tag with N-terminal thrombin-cleavage site containing recombinant BCL6 BTB domain C8Q/C67R/C84N/E99V ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetB-cell lymphoma 6 protein(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50366289(CHEMBL4163317)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to human BCL6 BTP domain assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMedPDB3D3D Structure (crystal)