BDBM50362100 CHEMBL1940501

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1nc(CCOCc2cccnc2)cs1)C(C)(C)C

InChI Key InChIKey=FNKUETGWXHXSHJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50362100   

TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50362100(CHEMBL1940501)
Affinity DataKd:  1.66E+3nMAssay Description:Binding affinity to N-terminus His-tagged human p38alpha expressed in Escherichia coli BL21 DE3 after 5 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Chemical Genomics Centre of The Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50362100(CHEMBL1940501)
Affinity DataIC50: 3.64E+3nMAssay Description:Inhibition of N-terminus His-tagged human p38alpha expressed in Escherichia coli BL21 DE3 using GST-tagged ATF2 as substrate after 90 mins by HTRF as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed