BDBM50361469 CHEMBL1938764

SMILES CCNC(=O)NCc1ccccc1Sc2ccc3nnc(n3c2)C(C)C

InChI Key InChIKey=PHHKWHBPRKFKKF-UHFFFAOYSA-N

Data  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361469   

TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50361469(CHEMBL1938764)
Affinity DataKd:  3.30nMAssay Description:Binding affinity to p38alpha MAPK by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50361469(CHEMBL1938764)
Affinity DataIC50: 58nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50361469(CHEMBL1938764)
Affinity DataKd:  3.30nMAssay Description:Binding affinity to P38alpha MAPK (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)