BDBM50358883 CHEMBL1923468

SMILES c1cc(cc2c1cc(cc2)Cl)S(=O)(=O)N[C@H]3CCCN(C3=O)CC(=O)N4C[C@@H]5C[C@H](C4)C6=CC=CC(=O)N6C5

InChI Key InChIKey=FLGSVBQCPOVGER-UHFFFAOYSA-N

Data  8 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50358883   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataIC50: 13nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  4.71nMAssay Description:Inhibition of human factor 10a by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.28E+3nMAssay Description:Inhibition of human TPA by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  3.28E+3nMAssay Description:Inhibition of human alpha-thrombin by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  3.68E+3nMAssay Description:Inhibition of human factor 7a by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.33E+4nMAssay Description:Inhibition of human factor 11a by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.51E+4nMAssay Description:Inhibition of human u-PA by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibition of human plasmin by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50358883(CHEMBL1923468)
Affinity DataKi:  2.25E+4nMAssay Description:Inhibition of human activated protein C by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed